The UK SPINE Knowledge Exchange aims to improve healthspan (healthy life-years) for patients with multiple age-related conditions.  Our mission is to accelerate the development and testing of potential new drugs and ensure the most promising treatments reach patients as quickly as possible. By better understanding the underlying biology which drives these conditions we can tailor drug development. This network, driven by six partner institutions throughout the UK, is committed to open sharing of knowledge, research and understanding of age-related illness.